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Statement on the antigen composition of COVID-19 vaccines
Clinical evaluation of relevant new vaccine antigens derived from more recent SARS-CoV-2 variants. As previously stated, the TAG-CO-VAC continues to encourage the further development of vaccines that may improve protection against infection and reduce transmission of SARS-CoV-2.
Efficacy and limitations of SARS-CoV-2 vaccines - A systematic review
The emergence of the SARS-CoV-2 virus worldwide led to the call for the development of effective and safe vaccines to contain the spread and effects o…
Statement on the antigen composition of COVID-19 vaccines
The WHO Technical Advisory Group on COVID-19 Vaccine Composition (TAG-CO-VAC) held its twice-yearly decision-making meeting in December 2025 to review the evolution of SARS-CoV-2, the performance of currently approved COVID-19 vaccines and the implications for COVID-19 vaccine antigen composition.
Efficacy of novel SARS-CoV2 vaccines in preventing SARS- CoV- 2 ...
Background Efficacious SARS-CoV-2 vaccines are urgently required to prevent the spread of the emerging and re-emerging SARS-CoV-2. Objective Aim to assess the efficacy of novel SRAS-CoV-2 vaccines in preventing SARS-CoV-2 infection. Methods All ...
Longitudinal analysis of immune responses to SARS-CoV-2 ... - Frontiers
The durability of vaccine-induced immune memory to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial for preventing infection, especially severe disease.
Induction of lung mucosal immunity by a next-generation ... - Nature
The current COVID-19 vaccines are suboptimal against the evolving SARS-CoV-2 variants, particularly in high-risk populations. A next-generation vaccine strategy capable of effective induction of respiratory mucosal immunity remains to be ...
Vaccine effectiveness across the Omicron evolutionary spectrum (BA.2 ...
Background Since late 2021, the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has undergone rapid evolutionary diversification, giving rise to successive subvariants with increasing immune escape. In response ...
Overview of COVID-19 Vaccines and Vaccination | Covid | CDC
Learn about types of COVID-19 vaccines and find recommendations, dosage, and overview of schedule.
A phase 1 clinical trial of a multi-antigen SARS-CoV DNA vaccine as a ...
The COVID-19 pandemic was controlled by active vaccination, but emergence of viral mutations in the receptor-binding domain (RBD) of the spike (S) pro…
mRNA-based seasonal influenza and SARS-CoV-2 multicomponent vaccine in ...
A multicomponent vaccine targeting several seasonal respiratory pathogens may provide simultaneous protection in a single-injection regimen. We present interim (28 days) findings from a phase 1/2 study of an mRNA-based multicomponent vaccine ...
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